Hidradenoma nodular maligno / Malignant Nodular Hidradenoma

Introducción: El hidradenoma nodular maligno es un tumor maligno de glándula sudorípara ecrinas, poco común, considerada una lesión de diferenciación anexial ecrinas, que generalmente surge de nuevo, aunque se han descrito unos pocos casos surgidos sobre un hidradenoma nodular. Es decir, representa la contrapartida maligna del hidradenoma nodular. Objetivo: Dar a conocer la presentación de un caso, dada la inusual aparición de esta entidad, con revisión de los criterios para su diagnóstico. Caso clínico: Se informa el caso de un hombre de 74 años de edad con una neo formación en la región parietal derecha del cuero cabelludo. Conclusiones: Debemos pensar en un hidradenoma nodular maligno ante un tumor solitario, firme o fluctuante, infrecuente en el cuero cabelludo, con curso agresivo, recurrencias y metástasis ganglionares y confirmar su diagnóstico con el estudio inmunohistoquímico(AU)

Introduction: Malignant nodular hidradenoma is a rare malignant eccrine sweat gland tumor considered a lesion of eccrine adnexal differentiation, which usually arises again, although a few arising cases on nodular hidradenoma have been described. In other words, it represents the malignant counterpart of nodular hidradenoma. Objective: To report a case, given the unusual occurrence of this entity, with a review of the criteria for its diagnosis. Case report: We report the case of a 74-year-old man with a neoformation in the right parietal region of the scalp. Conclusions: We should consider a malignant nodular hidradenoma when faced with a solitary, firm or fluctuant tumor, rare in the scalp, with aggressive evolution, recurrences and lymph node metastasis, and confirm its diagnosis with immunohistochemical study(AU)

Clear Cell Hidradenoma in a Young Male Nipple: A Case Report

PURPOSE: Clear cell hidradenoma, now regarded as an eccrine sweat gland tumor on the basis of its enzyme histochemical and electron microscopic features, occurs as a solitary tumor in most instances. METHODS: A 17 year old male presented with asymptomatic nodule, which had developed on nipple with a four years of history and total excision and purse-string suture was then performed. RESULTS: No recurrence was observed 2 months after excision. Histologically, it showed a well circumscribed tumor composed of characteristic clear epithelial cells which are focally arranged in glandular patterns. CONCLUSION: This case is unique in that the tumor developed on the young male nipple, unusual site and this report emphasizes the benefit of local excision to prevent recurrence of these tumor.

A Case of Recurrent Clear Cell Hidradenoma / 대한피부과학회지

Clear cell hidradenoma is a relatively rare benign cutaneous tumor. Treatment of choice is surgical excision but there have been some reports in Korea of recurrence of clear cell hidradenoma after surgical excision. We report a case of a 33-year-old woman with recurrent clear cell hidradenoma which recurred twice on her left anterior thigh. The first lesion was noticed 8 years ago and excised surgically 6 years ago. Three years after the operation, the lesion recurred on the operation site and was excised again. But 3 months ago the lesion appeared again, so we performed wide, complete excision and made a diagnosis of clear cell hidradenoma.

A Case of Malignant Clear Cell Hidradenoma / 대한피부과학회지

Malignant clear cell hidradenomas are rare tumors originating from the eccrine sweat gland. Usually, they are malignant from their inception, but some develop from benign nodular hidradenomas. Although there is insufficient evidence in the literature, the recurrence rate may be estimated at about 50%, and the metastasis rate is about 60%, including regional nodes, bone, viscera, and the skin. We report a case of malignant clear cell hidradenoma in a 63-year-old woman, who had a 3-year history of asymptomatic pea sized hard solitary nodules on the right forearm. Despite repetitive surgical excisions, the lesions were recurred 5 times. To our best knowledge this is the first case of malignant clear cell hidradenoma in the Korean dermatologic literature.

A Case of Clear Cell Hidradenoma Developing on the Scrotum / 대한피부과학회지

A 70-year-old man presented with an asymptomatic 1.5 x 2.5 cm sized lobulated mass with central ulcer on the scrotum. Histologically, it showed a well-circumscribed tumor composed of solid portions with fusiform basophilic cells and clear round cells, cystic spaces and tubular lumina, which were consistent with clear cell hidradenoma. Our case is unique in that the tumor developed on the scrotum, an unusual site.

A Case of Malignant Clear Cell Hidradenoma

Malignant clear cell hidradenoma is a rare eccrine gland malignancy characterized by a solitary nodule on the head, trunk or distal extremity. We report a case of malignant clear cell hidradenoma in the left sole of a 66 year old female patient. Despite wide resection, regional lymph node dissection and radiation therapy, wide spread regional invasion and multiple distant metastasis were developed. As the malignant clear cell hidradenoma is reported rarely in the world and not yet reported in Korea, we report its clinical process of the diagnosis and treatment to patient's death.

Four Cases of Clear Cell Hidradenoma / 대한피부과학회지

Clear cell hidradenoma is a relatively infrequent benign tumor that shows differentiation from or toward the structure of the eccrine sweat gland. We report four cases of clear cell hidradenoma which consists mainly of typical clear cells with small numbers of polyhedral cells. Clinically these tumors represented solitary erythematous firm nodular or cystic mass. In immunohistochemical study of one case, polyhedral cells rather than clear cells reacted positively for carcinoembryonic antigen and cytokeratin. We also review the previous reports of clear cell hidradenoma in Korean dermatologic literature.

Clear Cell Hidradenoma: Report of three cases

Clear cell hidradenoma, generally as an eccrine sweat gland origin, is a fairly uncommon tumor and occurs as a slowly growing, usually solitary nodule. The histological patterns vary from one tumor to another and in different parts of the same tumor. We experienced three cases of clear cell hidradenoma which were diagnosed by the histopathologic examination of the tumor mass removed by surgical excision. Clinical and histopathologic features of each case were reviewed and compared.

A Case of Clear Cell Hidradenoma / 대한피부과학회지

We report herein a case of clear cell hidradenoma in a 65-year-old man, who had a 8-month history of a asymptomatic, smooth-surfaced, round, blue tumor mass with cystic grape-like nature on the left upper chest, measuring 2.0 x 2.0 x 1.5cm in size. A histopathological examination revealed tubular and cystic structures within the intradermal tumor composed of predominant fusiform cells and clear cells, and some transitional cells. The patient remained free of recurrence for a period of one-year follow-up after the excision.

A Case of Appendage Tumor Combined with Eccrine Poroma , Clear Cell Hidradenoma and Syringocystadenoma Papilliferum as a Single Tumor / 대한피부과학회지

Because most of the benign skin appendage tumors arise from pluripotential cells that form during adult life and possess the potentiality of differentiating in more than one direction, combinations of several tumor types can occur. We report a case of combined with eccrine poroma, clear cell hidradenoma, and syringocystadenoma papilliferum as a single tumor in a 41-year-old male who had suffered from a tumor on posterior neck for 5 years. The tumor was a relatively oval shaped pedunculated, and rubbery hard mass, measuring 3.5*3.0* 1.3cm in size. The outer surface was variegated and covered with hair. The diagnosis was confirmed by histopathological findings and surgical excision was done.